How frequently should iodine supplementation be administered?

Iodine supplementation is typically recommended to be administered annually, especially in populations at risk for iodine deficiency. This frequency is based on several factors, including the relatively long half-life of iodine in the body's tissues and the body's ability to store small amounts of iodine over time. It ensures that individuals maintain adequate levels of iodine to support thyroid function, which is crucial for metabolic regulation and overall health.

In contrast, shorter intervals such as once a month, every three months, or once every two years may not be sufficient for maintaining optimal iodine levels, particularly for those at risk for deficiency. Monthly or tri-monthly supplementation could lead to excess intake and potential toxicity, while biennial administration might not provide enough iodine to support thyroid health throughout the year. Hence, annual supplementation strikes a balance between preventing deficiency and avoiding excess.