What can result from depleted liver stores of Vitamin A?

The depletion of liver stores of Vitamin A primarily affects eye health, leading to severe eye lesions. Vitamin A is crucial for maintaining proper vision, particularly in low-light conditions. It plays a significant role in the formation of rhodopsin, a pigment found in the retina that is necessary for the perception of light. When the body is deficient in Vitamin A, it can lead to a range of ocular issues, including night blindness and more severe conditions such as xerophthalmia, which involves dryness and lesions in the eyes. These eye lesions can result in serious, potentially irreversible damage to vision if not addressed promptly.

While the other options might relate to nutrition and health, they are not directly linked to the depletion of Vitamin A. Protein-energy malnutrition involves a lack of adequate protein and energy intake, anemia often relates to iron deficiency or vitamin B12 deficiencies, and Addison's disease is a disorder of the adrenal glands affecting hormone production. Therefore, focusing on Vitamin A’s impact yields the clear understanding that eye lesions are a significant and direct result of its deficiency.